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Home / Research / Departments / Department of Animal Health, Welfare and Nutrition / Disease mechanisms, -markers and -prevention / Projects finalised 2006

Projects finalised 2006

Avian antigen specific T-cells

The aim of the project was to initiate research on antigen specific T-cells reactive against avian viruses.

Responsible: Senior scientiest Helle Juul-Madsen

Project period: 01.04.2005 - 31.12.2006

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Biomarkers to improve health, production and reproduction in dairy cows (BIosens 3.1)

The aims of the project were 1) Identify and investigate new indicators for physiological imbalance to improve nutrient status and reproduction in dairy cows, 2) Identify and investigate new indicators for inflammation and immune status in dairy cows and 3) Identify and investigate new indicators for rumen acidosis and laminitis.

Responsible: Head of research unit Klaus Lønne Ingvartsen

Project period:

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Identification of relevant biological indicators in milk (Biosens 1.1)

Description: Continuous chemical analyses of selected milk samples for LDH, BOHB, urea and progesterone. Measurements are supporting developed biological models and will support further development of the understanding of disease occurrence in early lactation. Furthermore, the present project serves as a basis for other Biosens projects: Defining and securing a safe data stream from the KFC experimental farm. Handling a desirable identity-sorting-sample system and a potential of m...

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Integration of in-line milk measures to predict cow status (Biosens 2.1)

To develop nutritional diagnostic models based on in-line measurements in milk supplemented by available additional on farm measurements.These models are expected to be used in a commercial application as well as generating scientific publications.

Responsible: Senior scientist Nic Friggens

Project period: 01.01.2002 - 31.12.2006

Partners: Lattec I/S

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Diagnostics and improvement of udder health in future milk production systems

The overall objectives of this project are to 1) Identify factors influencing udder health of herds converting to automatic milking, 2) Improve methods for the detection of mastitic cows and pathogens and 3) Describe the lactational changes in surfactant protein D (SP-D) and phenotypic and genetic relationship between SP-D and mastitis.

The specific objectives are to:

Conc. 1

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Prevention of production diseases and reproduction problems through reduction of physiological imbalance in the dairy cow

The main purpose of the project is to develop the biological basis for minimizing the physiological imbalance in early lactation and thus reduce the risk of production diseases and reproduction problems through new "individual" feeding and management strategies. The research tasks of the project are:

To elucidate how the physiological imbalance, expressed by metabolic profiles and tissue turnover/metabolism, is affected by changes i...

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Post-weaning diarrhoea in piglets - preventive strategies in the suckling period

Post weaning diarrhoea (PWD) is considered one of the major welfare and production problems at weaning in Denmark.The objective of the project is to improve production, health and welfare of the weaned piglets while at the same time reducing the use of drugs. Furthermore, the objective of the project is to increase the fundamental knowledge on how to improve the robustness of weaned piglets to changes in nutrition, environment, and infection pressure. This includes stud...

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Gene expression and proteome analysis of cattle

The aim of this project is to establish post-genomictechnology platforms, and to use these technologies to find molecular markers for disease mechanisms in cattle. These technologies include mass spectrometry-based proteomics, and chip-based gene expression analyses.

Responsible: Senior scientist Emøke Bendixen

Project period: 01.01.2005 - 31.12.2006

Partners: Dept. of Gen...

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The ínfluence of environmental factors on the immunity and infection in fowl

The purpose of the project is to examine the influence of selected environmental factors and different genetic material on the development of the immune response, protection and infection course in connection with Infectious Bursal Disease (IBD) in poultry. The investigations will include constant or repeated exposure to selected environmental factors such as differences in light periods, stock density, temperature, and social stress as well as analysis of innate defenc...

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PhD-project: A pig model on health damaging stress


Stress constitutes the body’s first order of defence toward potential detrimental environmental influences. Exposure to aversive stimuli initiates a cascade of adaptive events. The events include reactions of the central nervous system (CNS), the autonomic nervous system, the neuroendocrine systems, and behaviour. The CNS is responsible for the perception of the stimuli and activation of an integrated response, which typically includes an uns...

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PhD-projekt: Disease prevention in poultry production - focus on natural defence mechanisms

Background: The industrialised poultry production can be characterised as a system in which infections are generally eliminated partly by the principle of “everything out – everything in” and partly by very high hygienic standards. The absence of infections implies that the animals do not develop an optimum immune response against potential infections. The utilisation of the animals’ ability to establish a defence against specific infections by means of natural immunisation has in...

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Selective breeding of pigs for resistance to clinical and subclinical disease during the piglet stage of commercial production

The general objective of this study is to test that selective breeding is a viable method to control clinical and sub-clinical disease (i.e., diarrhoea, respiratory problems, lameness, skin disorders) in pigs during the piglet stage of commercial production.

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Health in herds with automatic milking systems (AMS)

The purpose of the project is to create basic knowledge about prevention of production diseases and reproduction problems in ruminants, secondly to intensify DIAS’ research in AMS for the direct benefit of society and to improve DIAS’ international position in this field. The work will be based on the analysis of data generated by the automatic milking systems for optimum utilisation of existing databases. This comprises coupling of data directly from AMS with objective evaluations of he...

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Development of new methods for analysis of cellular immunity and assesment of protective immunity induced by Newcastle disease vaccination

The aim of this project is to contribute to improved assessment of protective immunity induced by Newcastle disease (ND) vaccination with focus on cellular immunity. In the project new reliable methods for analysis of ND specific immune cells will be established using vaccinated layers of different genetic background.

Responsible: Project scientist Tina Dalgaard

Project period: 01.01.2006 -...

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Improving poultry health - developing new methods to study cellular immunity to infectious diseases

Infectious diseases cause substantial problems in all types of poultry production. They pose a threat to animal welfare and create economic losses through mortality and loss of production. One of the most effective ways to combat infectious agents is to vaccinate the animals in order to render them immune to disease. Vaccination reduces the need for antimicrobial and coccidiostatic compounds during poultry rearing and is indeed the only prophylactic treatment allowed in organic rearing s...

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Organic egg production - strategies for immune stimulation under production conditions

The objective of the project is to develop health improving strategies for organic egg production that stimulate development and utilisation of the natural defence mechanisms against infections in animals thereby improving health and food safety. Knowledge on fundamental mechanisms in stimulation of the immune system by infection pressure and mild stress as well as methods suitable for organic egg production will be studied.

Responsible: Senior scientist

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